By understanding what is going on inside the brain during mania we can use self-help to develop effective self-help preventative and treatment solutions.

In manic phases, there are excess levels of the neurotransmitter glutamate and overactivity in second-messenger signalling in the  brain, in this vidio you will learn the two main things driving mania and how to combat them for both treatment and prevention.  

In manic phases, there are excess levels of the neurotransmitter glutamate and overactivity in second-messenger signalling in the brain.

Excess glutamate is produced in the brain By the brains immune cells in response to inflammation and stress.
There are many self-help things we can do to combat Both stress and sources of inflammation that cause the excessive build-up of glutamate the brain, and there are some things we can take to help reduce excess glutamate when it has built up.  

Reducing stress and some supplements can reduce the excessive 2nd messenger signalling within the nerve cells.

Together these self-help techniques could minimise the recurrence of manias and help shorten them when they occur.

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References and further reading:
Published: 11 June 2021
Inflammatory signaling mechanisms in bipolar disorder
Gregory H. Jones, Courtney M. Vecera, Omar F. Pinjari & Rodrigo Machado-Vieira
https://jbiomedsci.biomedcentral.com/...

Glycogen synthase kinase-3 in the etiology and treatment of mood disorders
Richard Scott Jope
PMID: 21886606 PMCID: PMC3152743 DOI: 10.3389/fnmol.2011.00016

The antimanic-like effects of andrographolide and quercetin
Thesis, Maastricht University, Universidade Federa do Paraná]. Maastricht University.
https://doi.org/10.26481/dis.20210322lk
Document status and date:
Published: 01/01/2021
DOI:
10.26481/dis.20210322lk

Review Published: 28 July 2010
Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?
Xiaohua Li & Richard S Jope
Neuropsychopharmacology volume 35, pages2143–2154 (2010)Cite this article

Stressed and Inflamed, Can GSK3 Be Blamed?
Richard S Jope 1, Yuyan Cheng 2, Jeffrey A Lowell 2, Ryan J Worthen 2, Yoel H Sitbon 2, Eleonore Beurel 2
PMID: 27876551 PMCID: PMC5336482 DOI: 10.1016/j.tibs.2016.10.009

Discovering protein kinase C active plants growing in Finland utilizing automated bioassay combined to LC/MS
Anna Galkin 1, Jouni Jokela, Matti Wahlsten, Päivi Tammela, Kaarina Sivonen, Pia Vuorela
PMID: 19370892

Effects of acute and chronic quercetin administration on methylphenidate-induced hyperlocomotion and oxidative stress
Luiz K S Kanazawa 1, Débora D Vecchia 1, Etiéli M Wendler 1, Palloma de A S Hocayen 1, Paulo S Beirão Jr 1, Manuela L de Mélo 1, Francislaine A Dos Reis Lívero 2, Claudia Rita Corso 2, Maria Carolina Stipp 2, Alexandra Acco 2, Roberto Andreatini 3
PMID: 28104366 DOI: 10.1016/j.lfs.2017.01.007