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RESIDENT EVIL 2 REMAKE 2nd RUN HARDCORE S+ GUIDE (Leon B Scenario Walkthrough)

Neon Slice

139,818 views

The EASY GUIDE for Resident Evil 2 Remake S+ Hardcore 2ND Run with Leon S. Kennedy. FULL WALKTHROUGH GUIDE to GET S+ Rank and unlock infinite ammo. HOW TO FINISH THE GAME IN UNDER 2 HOURS and with only up to 3 saves.
ALL PUZZLES - THE BEST ROUTES - THE BEST STRATEGY playthrough updated in 2024 by Neon Slice's professional S+ strategies!

[Timestamps]
0:00 Save 0
23:49 Save 1
56:25 Save 2
1:30:43 Save 3
1:43:34 Outro

RESIDENT EVIL 2 REMAKE HARDCORE S+ GUIDE (HOW TO GET S+ LEON): RESIDENT EVIL 2 REMAKE HARDCORE S+ GUIDE (...
(RESIDENT EVIL 2 HARDCORE NEON SLICE)

THIS IS NOT A SPEEDRUN.

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20 Comments

@NeonSlice Creator 2 years ago Pinned

Leon A Guide: https://youtu.be/CAxRgYFtIQU
[Timestamps]
0:00 Save 0
23:49 Save 1
56:25 Save 2
1:30:43 Save 3
1:43:34 Outro
:_NeonSliceSmilewesk:□

@Raaaissa 6 days ago

I wished I had this man’s peacefulness under pressure whenever I was trying to get an S+ on RE2 or RE4 😭

@zombinebrain 6 months ago

2026 still using this guide, thx❤

@Arte_de_jogar 5 months ago

Once again, bro carried me through another platinum in the RE franchise. I've been putting this one off ever since launch because I was afraid it would be too hard. But having your guides makes all the difference, thanks a lot!!

@kevinzavala8900 1 year ago (edited)

Gotta be honest. The B story with Leon is a giant pain in the butt. It took me a few days to complete because of so many attempts where I thought I took too long or something even though I would maybe get an S +. I just completed it and I want you thank you for this guide. I really appreciate your motivating words throughout the guide because trust me it really helps. Now I'm going to try to get S+ on Claire's B campaign. I know you made a guide about that so I'll use that. Again thank you. :)

@GamerGuyOG 2 years ago

Leon: POLICE! ON THE FLOOR! holds gun sideways

@SmokeyMarshmallows 11 days ago (edited)

Took me about five tries on save zero, but I've got it down to a science so far, will update as I go!
Save 1 complete

@jrschmitty6455 6 months ago

I was losing my mind trying to figure out how I was so behind despite following this walkthrough to a tee... I kept hitting retry instead of quit when I died. RIP. Oh well, at least I got the hardcore achievement and can go for the S ranking on regular.

@leshawnaspage 6 months ago

omfg your voice is soo calming thx for the guide

@MCeeWulphie 11 months ago

I like Neon Slice videos because he is mad calm and chill while he walks through the chaos explaining each instance in the game

@Chris_Lastname 1 year ago

The 2nd run hardcore's are real tough.
You made it look easy

@LEGLONN 5 months ago

hearing "Please do not use the rocket launcher here " right after using it there 😭😭😭😭😭

@alanwallis2467 1 year ago

Thanks for a great easy to follow walkthrough.you have certainly helped an older gamer (56 years old) Cheers from England.

@chrislomax9225 10 days ago

What'a guide, my new go to RE guy 🙏

@e-manyvelez7430 4 days ago (edited)

the part at 1:01:12 has got me stumped, no matter what I do the g grabs me. great guide though couldnt have made it this far without you

@spoonfedtruth7666 3 months ago

We're running 🏃 we're running stick to the left stick to the left we are running 😂 stick to the right! Youre the best! Did you see the preview for code Veronica! Claire looks amazing and it made me think of you cause you have a thing for her ❤

@Miles1675 1 month ago

Dude thanks so much without you I wouldn’t have completed the 100% Thanks again

@Ayesha-j8u 1 year ago

I left a comment on the wrong video earlier, just saying I tried this method of going upstairs first thing to get the keycard for the shotgun. I managed my first B-run S+. Slow players like me should definitely give it a try
Thanks again, Neon!

@jotajega 2 weeks ago

For those struggling with the greenhouse section while escaping from Mr. X, use your knife to slash the living plants laying in your path on the way to the bracelet, they will stay down on your way back.

@bigman42Bigman42 1 month ago

2026 using this guide it's very helpful your voice is very smooth and relaxing and calm. When I hear you talk I am not stressed playing this game I am calm 😅😅😅😅