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16 Celebs Who QUIT Ozempic and Gained It ALL Back | Before & After 2026

Spotlight ThenNow

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For two years, Hollywood only showed us the jaw-dropping transformations. But what happens the day the weight loss shots stop?
In this video, we uncover the hidden reality of quitting Ozempic, Mounjaro, and other GLP-1 medications through the very real experiences of 16 celebrities. From rapid weight regain and relentless hunger to severe side effects and the undeniable power of human biology, these stars reveal the truth the glossy magazines refuse to print.
Featuring the honest stories of Oprah Winfrey, Rebel Wilson, James Corden, Remi Bader, Sharon Osbourne, and more, we explore why stopping these medications is a much more complicated conversation than starting them. We look at the celebrities who rebounded hard, the ones who could not stop losing weight, and the medical emergencies no one saw coming.
The transformation is not the finish line. The maintenance is the entire game.

What to watch next: 24 Celebrities Suffering From Ozempic Face...

Disclaimer: The content provided in this video and description is for educational, informational, and entertainment purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition, prescription medication, or weight management plan. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this video.

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#Ozempic #WeightLoss #CelebrityNews #GLP1 #Mounjaro

20 Comments

@Marty-ii2ed 1 month ago

Best advice I ever got from public school French teacher…”Eat to live not live to eat”

@pambrown5401 1 month ago

How can you not know you are taking Ozempic? Don’t believe that for a minute.

@lindabrennan4455 1 month ago

I've lost 85lbs since last November 2025 by dieting. It's really difficult but I keep trying.

@SavannahCatMama 1 month ago

I haven’t heard of most of these people. Life is awesome when you don’t watch tv or have social media.

@RipsGirl 1 month ago

What's with the bullshit click bait thumbnail for this video? Nicole Kidman has never been that heavy 😑

@trishlangford5773 1 month ago

As with ALL strong drugs the consequences are terrifying.

@Arthur5260 1 month ago

These people, without exception, can afford to hire elite trainers. I was diagnosed w/ Type II Diabetes in 2022. I've been able to lose 30 lbs and reduce my A1C to pre diabetic levels by going to the gym and completely changing how I eat. The thought of losing my sight, kidney failure or amputation due to the disease keeps me inspired to eat right and stay online with this. I wouldn't touch these medications for anything.

@emme-9823 1 month ago

I’m using Ozempic to help with diabetics. It’s the only thing that has really helped with blood sugar control. It’s been a challenge when so many use this drug for weight loss when it’s not available who have medical need.

@Ninsidhe 1 month ago

Not just a diabetes medication- I’m on Mounjaro and for the first time in 45 years my inflammation markers are normal , the chronic body ache is gone, I can actually exercise without inflammatory side effects , my brain fog has improved drastically, there are so many benefits- I’d never go on Ozempic because it eats your muscles but on Mounjaro I’m thriving.

@TheQueenRulesAll 1 month ago

My partner was pressured by many to use this. Fortunately, he trusted my opinion over the others. He has finally taken it seriously and has already lost 20lbs with doet and exercise as well as reducing the stress around it all. It is rarely worth the potential side effects to use quick fixes for anything.

@silverfox5732 1 month ago

Wow I had actually made an appointment to start on this drug to lose 20lbs at age 67 ,thx for this video I went back and canceled that appointment, I'll keep trying and being me instead of losing something more that I need.

@BassBossÉire 1 month ago

Whoever goes to an "anti-aging Doctor" is not seeing an actual medical professional!

@lindabrennan4455 1 month ago

I took mounjaro for 1 month. I was not happy with the explosive diarrhea. It was a living nightmare.

@shirleyparker370 4 weeks ago

I am so grateful this story is out there!

@audrablue515 1 month ago

I was on Wegovy only for a month because the cost was crippling. I shed 4 kgs during the month and the food noise disappeared. I didn’t have any cravings going in. I just ate too much too frequently and my head was always thinking about food, how to get it, how to prep it, how much I could eat. After Wegovy, the food noise stayed gone and I haven’t gained any weight. But I haven’t lost any either. I’m generally eating well because I only eat food that I prep myself.

I don’t care about losing the weight any more. I’m staying as healthy as I can and watching my food volume and food types and I feel good.

@anneearley6328 1 month ago

I did GLP-1 for 7 weeks. I have never been more miserable, bloated, constipated, anxiety, couldn't sleep, couldn't breath, didn't lose weight. Went off it, stayed miserable for another 8 weeks. Ended up in the hospital and was diagnosed with congestive heart failure and Afib. Don't know if the drug is connected to my heart issues but I felt normal before GLP-1 then 10 days into it i was falling apart. I'm on 6 different drugs now for my heart and my heart is functioning at 26% instead of the normal 60%. I'm having to do low sodium, very low sodium and not drink more than 2 litres of liquid in a 24 hour period. I live in Arizona and i have to count every ounce of fluid I consume. I will never touch these drugs again.

@michaelmacpherson-wm6mh 1 month ago

got a checkup at 55 or so and all my numbers were borderline. stopped eating cookies, peanut butter, soda and fast food. cut down on beer and started walking and riding my bike and lost 50 pounds. at 66 I am still at 200lbs rather than 250.

@davids5048 1 month ago

"It is better to look good than to feel good." -- Billy Crystal playing Fernando Llamas on SNL
I guess they didn't realize he was joking.

@thedognoseknows4451 1 month ago

This is no surprise. Any quick weight loss thing is something you have to take for life. Why are these people so surprised.

@wolfwalker5924 1 month ago (edited)

Loosing the weight takes many off their daily: blood pressure meds, cholesterol meds, pain meds for knee joint pain exacerbated obesity and for many, dramatically lessening or eliminating insulin injections. Some are on all of them. So, staying on a maintenance dose or switching to other similar therapies i.e. retitrutide when available may be a choice that requires far fewer drugs with serious side effects for life. I'm anticipating staying on a version of this type of drug for life so as to be able to stay off the other side effect laden drugs several of which are associated with dimentia. Oh, I didn't mention that I have Graves so the bowel slowing is welcomed and a very slow heart rate normally in the 50s- low 60s. Trizepetide has helped.