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How Low Testosterone Secretly Destroys Your Health ft Dr. Mohit Khera

Rena Malik, M.D.

172,473 views

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Pre-order my new book The Hard Truth and get over $600 in FREE bonuses https://www.renamalikmd.com/hardtruth Pre-order The Hard Truth + get $494 in FREE bonuses (course, early chapters & live masterclass). https://www.renamalikmd.com/hardtruth Dr. Mohit Khera, renowned urologist, researcher, and expert in male and female sexual health, joins Dr. Rena Malik to discuss the global decline in testosterone, why symptoms matter more than blood test reference numbers, and the crucial role of free testosterone. They dive into types of testosterone replacement therapies—including injectables, gels, orals, and pellets—their risks, benefits, and considerations around fertility. The conversation also covers how semen analysis serves as a window into overall health, the influence of lifestyle changes (like weight loss, sleep, and stress management) on hormone levels, and the relationship between testosterone, cardiovascular health, depression, and prostate cancer. Dr. Khera and Dr. Malik explore regenerative therapies for erectile dysfunction, including hyperbaric oxygen, shockwave therapy, stem cells, PRP, and Botox, and discuss lesser-known issues such as post-finasteride syndrome and the status of sexual health in women.

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Chapters:
00:00:00 – Introduction
00:02:10 – The Testosterone Decline
00:06:07 – Free vs. Total Testosterone
00:11:32 – TRT Options
00:14:19 – Oral Testosterone & Fertility
00:17:26 – Protecting Fertility on TRT
00:20:38 – Recovery After TRT
00:29:10 – The Power of Estrogen
00:38:48 – Boosting Testosterone Naturally
00:42:31 – Stress & Operator Syndrome
00:50:12 – ED & Shockwave Therapy
00:55:13 – Regenerative Therapies
01:36:24 – Closing Thoughts

Watch the video till the end and let me know your thoughts in the comments.
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Rena Malik, MD is a urologist and pelvic surgeon on youtube to educate people about all things urology including erectile dysfunction, how to increase testosterone, problems with sex, premature ejaculation, urinary leakage, or incontinence, overactive bladder, urinary tract infections, prostate issues and more.

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▶️DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.
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20 Comments

@DimitriUSMC 1 year ago

Had all the classical symptoms of low T. While still exercising 5 times a week, lots of weightlifting, super clean diet, 12-14 percent body fat, 8 hours of sleep, and low stress. Still fit in same pants waist from my teens. However, felt like hell and it became an internal fight do anything physically, romantically, or sexually related. Total T was 480 and free was 7. At 1200 and 16 free, all the negative symptoms went away. Now even sleep improved, I dream again, can add muscle with ease and burn fat even easier. Testosterone brought back my my life in my 40's. Dont play the numbers game, play the symptoms in my opinion,

@juniormoraes14 1 month ago

I was going through a rough phase dealing with very low testosterone and almost no libido 🔥, and nothing I tried made a difference. The only thing that actually worked was a treatment I found in a video called “How Thompson Fixed ED” thanks, now I can last way longer, my wife thanks me a lot lmao

@BadCat1990 10 months ago

My total was 650 but my free was off the charts low. I’ve started a compounded cream twice and day and it has improved every aspect of my life. I feel amazing now.

@tonydawson22 1 year ago

At 39 I was tested. I wasn't sleeping, I was getting softer everywhere, and a libido was a relic from my past. I was moody, ill-tempered, and feeling more and more hopeless about the world around me like my 80 yr old granddad. My score was 167. I got started asap and every two weeks I was at that nurses station getting jabbed. Life had turned a wonderful page. Soon after they taught me to pin myself and all these years later (16) that's the only part I don't like. It gets old but the effects of the testosterone never do. I am so very thankful I took a friend's advice back in 2009.

@cryptojohnny7781 9 months ago

I fell in the 300 range and was always tired for years , just recently I got TRT treatment and wow I am no tired in the afternoons now. My number was 296 . Im only 3 weeks in and definetly feel the benifits

@PauloTravels 1 year ago

I'm on TRT for 6 years and I feel amazing. Prior I had depression, 0 libido, mental foggy, no drive whatsoever in life. I started having low T levels when I was 26 and found out what it was years later. I'm 35 now and TRT gave another boost to my life. I'm happy to feel like a real man should. I hated being a sensitive men!

@shortay153 10 months ago

Dr. Malik,You've made it!....when other Doctors on other channels quote you.... You've made it!....All the Best!

@GoldenEraBookworm 1 year ago

This has to be the best video I've ever seen on TRT. Thank you Drs

@maticulex5713 6 months ago

Had HORRIBLE OCD and anxiety for a year. Hindsight, decreased libido for several years too. Not non existent though. I was irritable and short. Brain fog and struggle focusing. I randomly, just to be cautious, decided to check my Testosterone. Never seriously considered it could be low. Total was at 400. Relaitvely low, i was surprised. Decided to check again but at 7am where it was supposed to be higher. To my surprise, it was 329. One more time to be sure. 336! My free T was very low at 3.6. I lift regularly, i sleep early, i eat healthy and avoid seed oils and processed food for the most part. I was shocked but also relieved thay my struggling mental health may be due to something other than just childhood trauma 😂

@ScottThomas-11a 1 year ago

I know myself and I’ve been on TRT for over 8 years. I can only speak for myself but have always felt my best when my range is around 850. I believe the normal ranges doctors recommend is too low. But each individual is different and that’s what’s important.

@drironmom6673 1 year ago

Great discussion. When I was in medical school, the reference range for testosterone was 750-1150. Now it’s 300-700. I use the old range. As both Drs. Kehera and Mali point out, symptoms and free testosterone are more important. So mostly I use symptoms, but we kinda have to check levels, and everyone gets fixated on the numbers.

@amitmahato3587 1 year ago

there’s this weird ache that comes from always being the guy who gets told “you’re so great, but…” i got sick of hearing it. i spent years thinking maybe i just wasn’t tall enough, rich enough, whatever enough. turns out, it wasn’t about any of that. it was the way i carried myself. the energy i gave off without even realizing it. a high school friend mentioned a book to me a while back and its called break her bed by jake black. it wasn’t hypey or weird, it just helped me see what i’d been blind to. definitely shifted something in me. Recommend everyone to give it a read.

@dewholdingsllc1050 1 year ago

Great content. Always best to hear from peer reviewed researchers.

@motonut007 1 year ago

Thank you?.... THANK YOU!!
This discussion today that I listen to is probably the best discussion that I've heard connecting the dots and relationships between testosterone estrogen and the medications and the receptors and everything else. I learned a lot from this discussion. This was really good. 😊

@lemartalang34 1 year ago

VERY SUBSTANTIAL TOPIC ..FEELING LUCKY TO BUMP IN THIS VIDEO..THANK YOU DOC

@jeremytjensvold9936 1 year ago

That was me! My total T dropped from 875 to 415 over the course of 7 years, had all of the symptoms of hypo G but my doctor (Kaiser) said they wouldn’t even do any further tests, let alone treat me until I hit 200ng/dl!! My free T was less than 0.5%

@husainismaeel2981 10 months ago

Thanks Dr. Rena and Dr. Mohit, very insightful.

Dr. Rena, I wonder if you could make a separate video dedicated for Post Finasteride Syndrome? It would be very helpful for a 5-year sufferer like myself.

@MrFredlthomasiii 1 year ago

Thanks for the information/topic Doc!!! Have a wonderful weekend!!!!❤

@bradleypierce5645 1 year ago

1:00:08 I wish my VA Doc would have looked at my testosterone!! I had to request to have it looked at because I just felt like trash all the time. Regardless of the meds they put me on for chronic depression and then anxiety meds on top of that. Nothing helped. Finally just went to a clinic outside of the VA and got things tested. Started TRT and 4 months later, I have completely stopped anxiety meds, and have reduced my depression meds by 75% of the dose I was on!!