Christina Applegate gets candid about self-esteem, MS, feeling alone in emotional interview

Good Morning America

Good Morning America

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Actress Christina Applegate is sharing new details about her battle with multiple sclerosis, and discussing whether her chronic condition will end her acting career.

Applegate, 54, told "Good Morning America" co-anchor Robin Roberts she has not yet accepted her MS diagnosis, which she announced in 2021.

"It still sucks, Robin. It really does," Applegate told Roberts in an interview that aired Tuesday on "GMA." "I have so many friends who have MS. And we talk to each other constantly. And I don't have one that says, 'I'm great.'"

"There is no great. There's a better day and a less s----- day," Applegate said. "This is a lifelong disease with no cure. Period."

0:00 - 1:26 Introduction

1:27 - 3:02 Shame

3:03 - 4:59 Abusive Relationship

5:00 - 7:09 Feeling Alone

7:10 - 10:16 Childhood

10:17 - 12:24 Dancing

12:25 - 17:58 Self-esteem

17:59 - 19:55 Success

19:56 - 21:28 'Anchorman'

21:29 - 23:21 Her Name

23:22 - 24:48 GMA '08 Intv.

24:49 - 27:26 MS Diagnosis

27:27 - 28:14 Her Daughter, Sadie

28:15 - 29:52 Names For Body Parts

29:53 - 30:23 Reality TV

30:24 - 31:00 Acting Future

31:01 - 31:41 Sadie

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