How Many of Your Pills Raise STROKE Risk After 65- 5 to Check Tonight!
Body Signals
25 views
You take them exactly as directed, and 5 ordinary drug classes still carry a stroke risk after 65. Here is the list to write down tonight.
After 65 your cardiovascular reserve narrows. Arteries stiffen, the baroreflex slows, the kidney loses range, and the vessels in your brain get slower to widen. Five everyday drug classes each spend a little of that margin, and the place a shortfall shows up is a vessel in the head. This episode counts them down from five to one, names the journal and the year behind every figure, and finishes with the twenty minute job that turns a shelf full of bottles into one written list and one sentence to say out loud at your next appointment. The evidence runs through the AGS Beers Criteria in the Journal of the American Geriatrics Society, The BMJ, Aging and Disease, the Archives of Internal Medicine, Therapeutic Advances in Drug Safety, JAMA Internal Medicine, and the FDA label change of 2015.
CHAPTERS
0:00 Why taking your pills correctly still carries risk
1:58 Cardiovascular reserve, the margin that narrows after 65
3:11 Number five, the one bought without a prescription
6:12 Number four and the blood number nobody plots
9:07 Number three, and the alarm that stops working
12:26 Number two, why an average is not you
15:31 Number one, the warning printed on the box
19:12 The written list and the sentence to say
SOURCES
American Geriatrics Society (2023). Journal of the American Geriatrics Society, AGS Beers Criteria: agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18372
Anticholinergic burden and acute cardiovascular events (2023). The BMJ: pmc.ncbi.nlm.nih.gov/articles/PMC10523277/
Concerns about diuretics as first line treatment in the elderly (2021). Aging and Disease: pmc.ncbi.nlm.nih.gov/articles/PMC8460303/
Salerno, Jackson and Berbano (2005). Archives of Internal Medicine: pubmed.ncbi.nlm.nih.gov/16087815/
Frier, Schernthaner and Heller (2011). Diabetes Care: diabetesjournals.org/care/article/34/Supplement_2/S132/28705/Hypoglycemia-and-Cardiovascular-Risks
Fanelli et al. (2017). Therapeutic Advances in Drug Safety: pmc.ncbi.nlm.nih.gov/articles/PMC5455842/
FDA Drug Safety Communication (2015). Non aspirin NSAID label strengthening: www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-strengthens-warning-non-aspirin-nonsteroidal-anti-inflammatory
Lapi et al. (2013). The BMJ, diuretics with ACE inhibitors and NSAIDs: www.bmj.com/content/346/bmj.e8525
Innes et al. (2024). JAMA Internal Medicine: jamanetwork.com/journals/jamainternalmedicine/fullarticle/2820722
Monahan et al. (2001). American Journal of Physiology, Heart and Circulatory Physiology: journals.physiology.org/doi/full/10.1152/ajpheart.2001.281.1.H284
Body Signals is general health information drawn from the studies linked above. It is not medical advice about you and not a reason to change anything you have been prescribed. Your own doctor knows your history.
#BodySignals #StrokeRisk #HealthAfter65
How Many of Your Pills Raise STROKE Risk After 65- 5 to Check Tonight!
Body Signals
25 views
You take them exactly as directed, and 5 ordinary drug classes still carry a stroke risk after 65. Here is the list to write down tonight.
After 65 your cardiovascular reserve narrows. Arteries stiffen, the baroreflex slows, the kidney loses range, and the vessels in your brain get slower to widen. Five everyday drug classes each spend a little of that margin, and the place a shortfall shows up is a vessel in the head. This episode counts them down from five to one, names the journal and the year behind every figure, and finishes with the twenty minute job that turns a shelf full of bottles into one written list and one sentence to say out loud at your next appointment. The evidence runs through the AGS Beers Criteria in the Journal of the American Geriatrics Society, The BMJ, Aging and Disease, the Archives of Internal Medicine, Therapeutic Advances in Drug Safety, JAMA Internal Medicine, and the FDA label change of 2015.
CHAPTERS
0:00 Why taking your pills correctly still carries risk
1:58 Cardiovascular reserve, the margin that narrows after 65
3:11 Number five, the one bought without a prescription
6:12 Number four and the blood number nobody plots
9:07 Number three, and the alarm that stops working
12:26 Number two, why an average is not you
15:31 Number one, the warning printed on the box
19:12 The written list and the sentence to say
SOURCES
American Geriatrics Society (2023). Journal of the American Geriatrics Society, AGS Beers Criteria: agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18372
Anticholinergic burden and acute cardiovascular events (2023). The BMJ: pmc.ncbi.nlm.nih.gov/articles/PMC10523277/
Concerns about diuretics as first line treatment in the elderly (2021). Aging and Disease: pmc.ncbi.nlm.nih.gov/articles/PMC8460303/
Salerno, Jackson and Berbano (2005). Archives of Internal Medicine: pubmed.ncbi.nlm.nih.gov/16087815/
Frier, Schernthaner and Heller (2011). Diabetes Care: diabetesjournals.org/care/article/34/Supplement_2/S132/28705/Hypoglycemia-and-Cardiovascular-Risks
Fanelli et al. (2017). Therapeutic Advances in Drug Safety: pmc.ncbi.nlm.nih.gov/articles/PMC5455842/
FDA Drug Safety Communication (2015). Non aspirin NSAID label strengthening: www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-strengthens-warning-non-aspirin-nonsteroidal-anti-inflammatory
Lapi et al. (2013). The BMJ, diuretics with ACE inhibitors and NSAIDs: www.bmj.com/content/346/bmj.e8525
Innes et al. (2024). JAMA Internal Medicine: jamanetwork.com/journals/jamainternalmedicine/fullarticle/2820722
Monahan et al. (2001). American Journal of Physiology, Heart and Circulatory Physiology: journals.physiology.org/doi/full/10.1152/ajpheart.2001.281.1.H284
Body Signals is general health information drawn from the studies linked above. It is not medical advice about you and not a reason to change anything you have been prescribed. Your own doctor knows your history.
#BodySignals #StrokeRisk #HealthAfter65