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The HRT Side Effect Nobody Warns You About | 5 Common Side Effects of Hormone Replacement Therapy

Jennifer Roelands, MD Perimenopause, Longevity

11,525 views

Are you starting Hormone Replacement Therapy (HRT) and wondering what to expect? In this video, Dr. Jen, a metabolic and hormone expert, breaks down the 5 common side effects of HRT and explains why they happen, when to be concerned, and how to work with your doctor to find the right balance for your body.

Whether you're in perimenopause or postmenopause, understanding how estrogen and progesterone affect your body is key to a successful hormone journey. We cover everything from irregular bleeding to mood changes and even why you might feel like your HRT "isn't working."

In this video, you’ll learn: ✅ Why irregular bleeding or spotting occurs in the first 6 months. ✅ The connection between estrogen, progesterone, and breast tenderness. ✅ How HRT impacts mood, anxiety, and depression. ✅ Why oral progesterone might be making you too sleepy. ✅ What to do if you feel like your hormone therapy isn't working.

Hormone replacement therapy can be life-changing for managing hot flashes, brain fog, joint pain, and energy levels, but it’s not a one-size-fits-all solution. Watch to learn how to be your own health advocate!

📌 For more menopause and hormone health content, subscribe here @drjenniferroelandsmd

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TAKE MY FREE QUIZ ARE YOU IN PERIMENOPAUSE? https://precisionhealthmdoc.com/perim...
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I'm Dr. Jennifer Roelands, a double-board-certified OB/GYN and integrative healthcare provider based in California. I practice precision, functional, and integrative medicine. What does that mean? I look at an individual's genetics, environment, and lifestyle, and together, we design ways to optimize health, function, and performance. It's not one-size-fits-all but a way to personalize your nutrition, sleep, stress levels, inflammation, detoxification, and hormone balance.

👩🏻‍⚕️I see patients in my private telemedicine practice in many states, and my practice is growing. You can become a patient and book your visit here: https://precisionhealthmdoc.com/.

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As always, this is not meant to be direct medical advice; my videos are for educational purposes only. These options are my own.

Disclaimer: This is not direct medical advice. These opinions are my own and don't represent those of my institution. These videos are for educational purposes only.

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Timestamps:

[00:00] - Introduction: What to expect with HRT
[00:42] - Side Effect #1: Irregular Bleeding & Spotting
[02:40] - Side Effect #2: Breast Tenderness (Mastodynia)
[03:26] - Side Effect #3: Moodiness, Anxiety & Irritability
[04:39] - Side Effect #4: Feeling Too Sleepy or Groggy (Progesterone)
[06:05] - Side Effect #5: Why it feels like it’s NOT working
[07:09] - How to find the right HRT regimen for you

#HRT #HormoneReplacementTherapy #Perimenopause #MenopauseHealth #HormoneBalance #WomensHealth #MenopauseSymptoms #Progesterone #Estrogen #DrJenRoelands

20 Comments

@drjenniferroelandsmd Creator 9 days ago Pinned

📖 Ready to go deeper? Pivot: Your Perimenopause Playbook → https://www.amazon.com/Pivot-Perimenopause-Playbook-Jennifer-Roelands/dp/1662975848/

🌸 Looking for practical guidance to better understand your symptoms? Get the How to Talk to Your Doctor Guide → https://drjenniferroelands.com/guide/

@marjayhan75 1 month ago

It took me a while to learn that you don’t gain weight on hrt. You get increased appetite. Those are two different things. If you have had your meal, and find an hour later that you are hungry, don’t listen to it! Or stave it off with something seriously low calorie like a plain cracked broken in small bits or a couple of cucumber slices chopped into little bits. I gained 50lbs over 3 years not knowing I was perimenopause as it wasn’t mentioned by the doctor. I was put on anti depressants which increased my hunger hormone. I managed to lose 30lbs over the next 2 years after being put on various methods of hrt. Still have 20lbs to go but now I ask myself “is this true hunger?”when I get hunger pains now. It’s not real if I have a good breakfast, and then 2 hours later I’m hungry again. It’s just hormones. We need to learn to switch that off in our minds. Hope this helps someone. Cos I just realised it after i gained all the weight, blaming the medications instead of making the connection that I answered every little hunger pain with food.

@PotatoWisdom 1 year ago

I'm surprised you didn't mention heartburn as a common side effect with oral Prometrium.

@reneedieuvil70 7 months ago

This dr, by far, gave the best explanation. She answered all my questions. Some people on YouTube like to just hear themselves talk. This Dr. Git straight to the point, and I'm grateful. I followed her.

@liudmylagrytsiv5061 9 months ago

What about bloating, puffiness and extreme appetite?

@Roshe73 8 months ago (edited)

Hot body , heart palpitations heart racing , rage , headache and head heavy can’t sleep, increased appetite, bloating, blurry eyes- 6 weeks in . I’m battling how long does it take to settle. I’m 52 anxiety, it’s not working. I not even sleeping restless and feeling sick.

@patriciachristiansen-o9n 2 weeks ago

i have struggled for 7 years …i started estrogen pill and it worked great for the hot flushes which are my main problem as they disturb sleep a lot. but after a couple years i started to get upper abdominal ‘discomfort’ which gradually became constant and felt like an ulcer. i stopped the hrt and it immediately fixed that symptom, but within a week the hot flushes returned. over the next several years i have tried topical gels and patches of various strengths, but the ulcer like symptoms came back. i then tried adding micronised progesterone (even though i had a hysterectomy) and that worked for about a year but again the gut burning started again. went off all het a month ago and no gut issues. i want to keep on hrt for bone strength, skin, hair and vitality but looks like it’s not for me😢

@monikakress3867 7 months ago

combi patch progesterone turned me into a raging pms monster.

@Terri1373 2 months ago

I've just started on the lowest dose of hrt.
Evorel patch and utrogestan 100mg.
I'm only having feelings of being hot and a bit sweaty.
My sleep is actually better. I wasn't sleeping well at all before. I don't feel groggy in the morning. I feel a bit tired in the afternoon, but that's normal for me.
Hoping i dont gain weight.

@emmabrown3582 4 months ago

Yes it was very helpful especailly with the pain around my lady bits and the dryness near my lady bits and with the bad headaches and spotting and me being grumpy and feeling sad poorly sometimes before I start a period

@deeveriamoore2205 1 year ago

Thanks for sharing I'm considering HRT

@tarared7668 3 weeks ago

Be careful ladies, hrt is not for everybody. I stopped after 24 days of horrible side effects, not for me😢

@denisefuentes7905 1 month ago

They are all good for me.

@eleonorarigovic7551 1 year ago

Forgot to add i am 66 and on 1 pump of oestrogel and little test compounded cream. Thanku

@lucnchuc824 1 month ago

My blood pressure is dropping. 100/50 I came off my blood pressure medicine now I just got to get it in a normal range

@79awa 5 months ago

I hated it i felt like a balloon low energy n worse then i did before it..

@maplenook 5 months ago

Anemia from blood loss, had to stop HRT, not clear if I can restart with new approach such as cycling.

I was not absorbing the estradiol from injections, patches or creams. Levels 12-25

@emmabrown3582 4 months ago

And i do iche around my ears and i do get hot too during the day and at night and i hurt near boobs too and i have joint pain and i have hard poo and Im 38 and my mouth always feels hot ect perimenopause iam talking is it possible I might have the start of it?