¿Qué hace realmente el amlodipino dentro de tu cuerpo?
Dr. Alberto Sanagustín
266,993 views
Do you take amlodipine for high blood pressure? If you've been told it's mandatory to take it at night or you've been alarmed by swollen ankles, science has already proven these are myths. In this video, I'll explain in a very simple way how this medication works in your body, why grapefruit is off-limits in your diet, and what the critical mistake is that you should never make when you see that your blood pressure is back to normal.
0:00 Why take amlodipine?
0:49 What is amlodipine and what is it used for?
1:14 How does amlodipine work?
1:40 How long does it take to take effect and keep blood pressure stable?
2:09 What is the best time to take it? (The TIME study)
2:58 What happens if I forget to take the pill?
3:45 Why do ankles swell? 4:38 Can it cause hot flashes or itchy legs?
5:16 Can it damage or bleed gums?
5:39 Does it have long-term side effects or cause dependence?
6:15 Does this pill cause weight gain or affect weight?
6:33 Does it affect the head, sleep, fatigue, or memory?
7:02 Does it damage the kidneys or help protect them?
7:34 Can you drive, ride a bike, or carry on with your normal activities?
8:03 Is it dangerous to combine it with grapefruit?
8:51 What happens if I drink alcohol while taking amlodipine?
9:15 Can it be taken with other blood pressure medications?
10:03 Can amlodipine cause a dry cough? (Confusion with "-pril")
10:46 Mixing amlodipine and simvastatin (cholesterol): Is it dangerous?
11:46 The critical error: Can I stop taking the pill if my blood pressure is fine?
12:47 The Health Traffic Light: When is it normal and when should I go to the ER?
14:18 Can lifestyle changes replace the pill?
15:31 Recommended video
Dr. Alberto Sanagustín
References
Mackenzie IS, Rogers A, Poulter NR, Williams B, Brown MJ, Webb DJ, Ford I, Rorie DA, Guthrie G, Grieve JWK, Pigazzani F, Rothwell PM, Young R, McConnachie A, Struthers AD, Lang CC, MacDonald TM; TIME Study Group. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomized, open-label, blinded-endpoint clinical trial. Lancet. 2022 Oct 22;400(10361):1417-1425. doi: 10.1016/S0140-6736(22)01786-X. Epub 2022 Oct 11. PMID: 36240838; PMCID: PMC9631239.
https://www.thelancet.com/journals/la...
Makani H, Bangalore S, Romero J, Wever-Pinzon O, Messerli FH. Effect of renin-angiotensin system blockade on calcium channel blocker-associated peripheral edema. Am J Med. 2011 Feb;124(2):128-35. doi: 10.1016/j.amjmed.2010.08.007. PMID: 21295192.
https://pubmed.ncbi.nlm.nih.gov/21295...
Messerli FH. Vasodilatory edema: a common side effect of antihypertensive therapy. Curr Cardiol Rep. 2002 Nov;4(6):479-82. doi:10.1007/s11886-002-0110-9. PMID: 12379167.
https://pubmed.ncbi.nlm.nih.gov/12379...
Bailey DG, Dresser G, Arnold JM. Grapefruit-medication interactions: forbidden fruit or avoidable consequences? CMAJ. 2013 Mar 5;185(4):309-16. doi: 10.1503/cmaj.120951. Epub 2012 Nov 26. PMID: 23184849; PMCID: PMC3589309.
https://www.cmaj.ca/content/185/4/309
UK National Health Service (NHS). Amlodipine: medicine to treat high blood pressure.
https://www.nhs.uk/medicines/amlodipine/
Spanish Agency for Medicines and Health Products. Technical Data Sheet: Amlodipine. CIMA, AEMPS
https://cima.aemps.es/cima/dochtml/ft...
★ The videos on this channel are for informational purposes only. They are not intended to replace direct medical advice. If you have or think you have any symptom, sign, or illness described in these videos, you should always consult your doctor. Nothing can replace the direct doctor-patient relationship.
⚠️ All my public activity is solely on my official channels and the verified links in the Linktree of this profile: https://linktr.ee/alsanagust
Any advertisement, page, comment, or video that uses my image or name outside of my official channels is false.
★ NOTE: This channel may occasionally use AI-generated images for illustrative purposes; they do not represent actual clinical facts.
20 Comments
Llevo dos años con ello y no se me hinchan los tobillos ni he notado nada raro.
En la última visita al cardiólogo, que me ha dado tres años de vacaciones de visitas,me dijo que mi corazón estaba sano, no hay necrosis.
Pero también me dijo: tratamiento o muerte.
¿Qué hace realmente el amlodipino dentro de tu cuerpo?
Dr. Alberto Sanagustín
266,993 views
Do you take amlodipine for high blood pressure? If you've been told it's mandatory to take it at night or you've been alarmed by swollen ankles, science has already proven these are myths. In this video, I'll explain in a very simple way how this medication works in your body, why grapefruit is off-limits in your diet, and what the critical mistake is that you should never make when you see that your blood pressure is back to normal.
0:00 Why take amlodipine?
0:49 What is amlodipine and what is it used for?
1:14 How does amlodipine work?
1:40 How long does it take to take effect and keep blood pressure stable?
2:09 What is the best time to take it? (The TIME study)
2:58 What happens if I forget to take the pill?
3:45 Why do ankles swell? 4:38 Can it cause hot flashes or itchy legs?
5:16 Can it damage or bleed gums?
5:39 Does it have long-term side effects or cause dependence?
6:15 Does this pill cause weight gain or affect weight?
6:33 Does it affect the head, sleep, fatigue, or memory?
7:02 Does it damage the kidneys or help protect them?
7:34 Can you drive, ride a bike, or carry on with your normal activities?
8:03 Is it dangerous to combine it with grapefruit?
8:51 What happens if I drink alcohol while taking amlodipine?
9:15 Can it be taken with other blood pressure medications?
10:03 Can amlodipine cause a dry cough? (Confusion with "-pril")
10:46 Mixing amlodipine and simvastatin (cholesterol): Is it dangerous?
11:46 The critical error: Can I stop taking the pill if my blood pressure is fine?
12:47 The Health Traffic Light: When is it normal and when should I go to the ER?
14:18 Can lifestyle changes replace the pill?
15:31 Recommended video
Dr. Alberto Sanagustín
References
Mackenzie IS, Rogers A, Poulter NR, Williams B, Brown MJ, Webb DJ, Ford I, Rorie DA, Guthrie G, Grieve JWK, Pigazzani F, Rothwell PM, Young R, McConnachie A, Struthers AD, Lang CC, MacDonald TM; TIME Study Group. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomized, open-label, blinded-endpoint clinical trial. Lancet. 2022 Oct 22;400(10361):1417-1425. doi: 10.1016/S0140-6736(22)01786-X. Epub 2022 Oct 11. PMID: 36240838; PMCID: PMC9631239.
https://www.thelancet.com/journals/la...
Makani H, Bangalore S, Romero J, Wever-Pinzon O, Messerli FH. Effect of renin-angiotensin system blockade on calcium channel blocker-associated peripheral edema. Am J Med. 2011 Feb;124(2):128-35. doi: 10.1016/j.amjmed.2010.08.007. PMID: 21295192.
https://pubmed.ncbi.nlm.nih.gov/21295...
Messerli FH. Vasodilatory edema: a common side effect of antihypertensive therapy. Curr Cardiol Rep. 2002 Nov;4(6):479-82. doi:10.1007/s11886-002-0110-9. PMID: 12379167.
https://pubmed.ncbi.nlm.nih.gov/12379...
Bailey DG, Dresser G, Arnold JM. Grapefruit-medication interactions: forbidden fruit or avoidable consequences? CMAJ. 2013 Mar 5;185(4):309-16. doi: 10.1503/cmaj.120951. Epub 2012 Nov 26. PMID: 23184849; PMCID: PMC3589309.
https://www.cmaj.ca/content/185/4/309
UK National Health Service (NHS). Amlodipine: medicine to treat high blood pressure.
https://www.nhs.uk/medicines/amlodipine/
Spanish Agency for Medicines and Health Products. Technical Data Sheet: Amlodipine. CIMA, AEMPS
https://cima.aemps.es/cima/dochtml/ft...
★ The videos on this channel are for informational purposes only. They are not intended to replace direct medical advice. If you have or think you have any symptom, sign, or illness described in these videos, you should always consult your doctor. Nothing can replace the direct doctor-patient relationship.
⚠️ All my public activity is solely on my official channels and the verified links in the Linktree of this profile: https://linktr.ee/alsanagust
Any advertisement, page, comment, or video that uses my image or name outside of my official channels is false.
★ NOTE: This channel may occasionally use AI-generated images for illustrative purposes; they do not represent actual clinical facts.
ÍNDICE
0:00 ¿Por qué tomar amlodipino?
0:49 ¿Qué es y para qué se usa el amlodipino?
1:14 ¿Cómo funciona el amlodipino?
1:40 ¿Cuánto tarda en hacer efecto y mantener la presión estable?
2:09 ¿Cuál es la mejor hora para tomarlo? (El estudio TIME)
2:58 ¿Qué pasa si me he olvidado de tomar la pastilla?
3:45 ¿Por qué se hinchan los tobillos?
4:38 ¿Puede provocar sofocos o picor en las piernas?
5:16 ¿Puede dañar o sangrar las encías?
5:39 ¿Tiene efectos malos a largo plazo o produce acostumbramiento?
6:15 ¿Esta pastilla engorda o altera el peso?
6:33 ¿Afecta a la cabeza, al sueño, al cansancio o a la memoria?
7:02 ¿Daña los riñones o ayuda a protegerlos?
7:34 ¿Se puede conducir, andar en bicicleta o hacer vida normal?
8:03 ¿Hay peligro al combinarlo con el pomelo (toronja)?
8:51 ¿Qué pasa si consumo alcohol mientras tomo amlodipino?
9:15 ¿Se puede tomar junto a otros medicamentos para la tensión?
10:03 ¿El amlodipino puede dar tos seca? (confusión con los "-pril")
10:46 Mezclar amlodipino y simvastatina (colesterol): ¿Es peligroso?
11:46 El error crítico: ¿Puedo dejar la pastilla si la presión ya sale bien?
12:47 El Semáforo de Salud: ¿Cuándo es normal y cuándo debo ir a urgencias?
14:18 ¿Los cambios en el estilo de vida pueden sustituir a la pastilla?
15:31 Vídeo recomendado