Testosterone, Mast Cells & Menopause: What Women Aren't Being Told
Dr. Kelly Casperson, M.D.
24,554 views
🎙️ In this episode of You Are Not Broken, Dr. Kelly Casperson sits down with Dr. Carrie Cashel (Instagram: drcericashell) to explore the overlooked connections between testosterone, mental health, and women's wellness.
From the impact of hormones like testosterone and DHEA on brain health to the hidden role of mast cell activation syndrome (MCAS) in unexplained symptoms, this conversation dives deep into the medical mysteries that affect women in midlife and beyond. Discover how cultural taboos and outdated beliefs are holding women back—and what you can do to advocate for better care.
🧠 *Topics Covered:*
Testosterone’s role in women’s mental and sexual health
Why mast cell activation might explain “mystery” symptoms
The mental health–hormone connection
What you need to know about vaginal DHEA
How curiosity in medicine leads to better outcomes
The truth about lifestyle changes, advocacy, and access to treatment
*Chapters*
00:00 Introduction and Background
04:53 Testosterone and Women's Health
09:37 Gender Bias in Sexual Health
16:20 Dementia and Women's Health
18:52 The Role of Estrogen in Bone Health
23:23 The Evolution of Menopause Care
27:58 The Impact of Hormones on Mental Health
31:40 Exploring Mast Cells and Their Role in Women's Health
36:33 Identifying and Managing Mast Cell Activation Syndrome
38:11 Lifestyle Changes and Treatment Options for Mast Cell Activation
42:46 Real Patient Stories and the Importance of Listening
48:31 The Connection Between SSRIs and Mast Cell Activation
50:37 The Need for Holistic Approaches in Women's Health
51:25 Vaginal DHEA and Hormonal Treatments in Australia
https://drcericashell.com/
https://www.healthyhormones.au/
Petition to Give Women Access to Affordable Testosterone Treatment: Put AndroFeme on the PBS (Australia): https://www.change.org/p/give-women-a...
———————————————
Subscribe: @kellycaspersonmd
Dr. Kelly Casperson is a board-certified urologic surgeon, sex educator, and CEO of The Casperson Clinic, specializing in hormones, sexual health, and midlife wellness. This channel is your go-to resource for science-backed insights on intimacy, desire, and thriving in midlife.
Through expert advice and candid conversations, Dr. Kelly helps women overcome myths about sexual health, demystify hormones, and create fulfilling relationships. Whether you’re navigating menopause, seeking to improve intimacy, or simply want to prioritize your health, this channel offers practical tips to help you live confidently and vibrantly.
Fix Your Sex Life with the book You Are Not Broken: Stop “Should-ing” All Over Your Sex Life – https://a.co/d/h8SOIrV
#youarenotbroken #drkellycasperson #hormonetherapy
Let’s Connect...
Website: https://www.kellycaspersonmd.com
Podcast: https://open.spotify.com/show/4iZ4pa5...
IG: Instagram: kellycaspersonmd
FB: Facebook: youarentbroken
Threads: https://www.threads.net/@kellycaspers...
Substack: https://substack.com/@kellycaspersonmd
Subscribe: @kellycaspersonmd
20 Comments
He shares in that book ways to address underlying gut problems. If we are missing key bacteria that process histsmines properly then we will have histamine reactions. Does that mean we need to eat a small window of foods forever? No. Means we need to restore the lost gut bacteria ( lost through glypgosate, antibiotic exposure & toxins) and heal the gut. Many many peopke are getting well learning what he has to share & trying some of what he recommends!
Dr Tina Peers is a U.K. doctor well versed in MCAS and HRT.
The Maudsley ( famous psychiatric hospital in U.K.) has published Deprescribing Guidelines for Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs.
Dr Dale Bredesen is a US doctor who wrote The End Of Alzheimer’s and has published papers on reversal of cognitive decline- he strongly advocates for 3 hormone HRT.
She has been on anxiety meds for over 1 year. i will have to make sure her doctor listens to this podcast before they try to wean off the ssri.
all the teens and postpartum women who suffer from sex hormone induced depression and/or anxiety. All they are offered is birth control pills and anxiety meds. While those might be needed for some and are life savers, many should get their hormones thoroughly screened and help offered.
I’ve recently decided to join the advocacy/activist(🙂) ranks to RAISE AWARENESS of our treatment options as women! I’m the elder-x, turning 60 this year, and I literally fell apart after my 59th birthday! Hopefully it saved my life! I’ve learned so very much from you (and some others!) My husband says I must have a Masters in Casperson by now! (He may or may not jokingly roll his eyes when he hears your voice 😂)
As I start my journey, I WILL be referring to having a Masters in Casperson!
Keep up the good work! ❤
For myself, I can't do antihistamines as I have a paradoxical response to them due to my ADHD. So I do NAC, querticin, vit c, D3K2 and mag glycinate. No leftovers. Whole foods only. Daily exercise. Doing all those things and estradiol and progesterone have greatly improved my quality of life.
I'm beyond grateful and fortunate for you & the posse ... I wish my mom had a version of you ... .
Or wait, SHBG and PMDD. And overall, just the fff that the pill does to us.
Testosterone, Mast Cells & Menopause: What Women Aren't Being Told
Dr. Kelly Casperson, M.D.
24,554 views
🎙️ In this episode of You Are Not Broken, Dr. Kelly Casperson sits down with Dr. Carrie Cashel (Instagram: drcericashell) to explore the overlooked connections between testosterone, mental health, and women's wellness.
From the impact of hormones like testosterone and DHEA on brain health to the hidden role of mast cell activation syndrome (MCAS) in unexplained symptoms, this conversation dives deep into the medical mysteries that affect women in midlife and beyond. Discover how cultural taboos and outdated beliefs are holding women back—and what you can do to advocate for better care.
🧠 *Topics Covered:*
Testosterone’s role in women’s mental and sexual health
Why mast cell activation might explain “mystery” symptoms
The mental health–hormone connection
What you need to know about vaginal DHEA
How curiosity in medicine leads to better outcomes
The truth about lifestyle changes, advocacy, and access to treatment
*Chapters*
00:00 Introduction and Background
04:53 Testosterone and Women's Health
09:37 Gender Bias in Sexual Health
16:20 Dementia and Women's Health
18:52 The Role of Estrogen in Bone Health
23:23 The Evolution of Menopause Care
27:58 The Impact of Hormones on Mental Health
31:40 Exploring Mast Cells and Their Role in Women's Health
36:33 Identifying and Managing Mast Cell Activation Syndrome
38:11 Lifestyle Changes and Treatment Options for Mast Cell Activation
42:46 Real Patient Stories and the Importance of Listening
48:31 The Connection Between SSRIs and Mast Cell Activation
50:37 The Need for Holistic Approaches in Women's Health
51:25 Vaginal DHEA and Hormonal Treatments in Australia
https://drcericashell.com/
https://www.healthyhormones.au/
Petition to Give Women Access to Affordable Testosterone Treatment: Put AndroFeme on the PBS (Australia): https://www.change.org/p/give-women-a...
———————————————
Subscribe: @kellycaspersonmd
Dr. Kelly Casperson is a board-certified urologic surgeon, sex educator, and CEO of The Casperson Clinic, specializing in hormones, sexual health, and midlife wellness. This channel is your go-to resource for science-backed insights on intimacy, desire, and thriving in midlife.
Through expert advice and candid conversations, Dr. Kelly helps women overcome myths about sexual health, demystify hormones, and create fulfilling relationships. Whether you’re navigating menopause, seeking to improve intimacy, or simply want to prioritize your health, this channel offers practical tips to help you live confidently and vibrantly.
Fix Your Sex Life with the book You Are Not Broken: Stop “Should-ing” All Over Your Sex Life – https://a.co/d/h8SOIrV
#youarenotbroken #drkellycasperson #hormonetherapy
Let’s Connect...
Website: https://www.kellycaspersonmd.com
Podcast: https://open.spotify.com/show/4iZ4pa5...
IG: Instagram: kellycaspersonmd
FB: Facebook: youarentbroken
Threads: https://www.threads.net/@kellycaspers...
Substack: https://substack.com/@kellycaspersonmd
Subscribe: @kellycaspersonmd