I used to do drugs. I still do, but I used to too.  - Mitch Hedberg

As an experienced drug professional,  the not sleeping psychosis is 100% accurate. Not sleeping only 1 day is manageable, after that- shit gets weird and difficult real quick.

I love the was a big upper guy and pro cocaine block text, lmao.

As someone in my mid 40s who ate a tab of acid last night, I feel better about myself.

Natasha's train of thought is marvelously chaotic

Former rock and roller.  I finally have 6 years+ sober.  Thank you Musicares.❤

Two Fat Slags. Thats a reference i was not expecting!!! 😂

I love Natasha Lyone. I'm so glad she's alive.

I really hope people don’t do drugs after watching this. Please be careful, be grateful to your mom that she gave you a life of health

the craziest thing about sleep deprivation is the change of perception. days without sleep and all of a sudden everybody is out to get you😂

There are some of us, even as adults, who can’t do drugs. Because by the next week, we will blow up our lives. But more power to you if you can.

I never thought I'd say this but let David Cross talk, Neal 😂

As someone who can't even do weed without having anxiety attacks, i'm oddly fascinated by people like these who can go deep into the hard stuff for a long time, and somehow make it out alive. It seems like fun...until it isn't.

Thank you for being open with your drug use. So very important for the future of our drug use rights.

My drug talk from my mother, when I was about 14, went like this
" Life is hard. It's normal to be depressed. As long as u can still handle your business, do whatever gets you through the day"
So no matter what I'd been doing all night/day, I still always went to work. Because it wasn't a problem as long as I didn't miss work. Lol. Ppl I partied with were always amazed. But it helped circumvent the guilt

Fuckin love Natasha she seems like such a cool human being

“which is weird cause i’m 22” i’m dead 10:12

I have such a huge crush on Natasha Lyonne

I LoVE her (Natasha) She is such a soul sister.

I remember an interview with Joel McHale where he told a story about buying his parents weed, one of the funniest things I've ever heard