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Dutasteride 2.5mg — The Clinical Data Nobody Is Talking About!

Anagen

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Most people treating hair loss with dutasteride assume 0.5mg is the ceiling. The blood test numbers seem to back that up — at 0.5mg you are already suppressing DHT by over 90%, so what would taking five times that dose even accomplish?

Turns out, quite a lot. But not for the reason most people assume.

A major clinical trial put this exact question to the test, and the results surprised researchers. One group grew significantly more hair than every other group in the study. Not because they were on a new drug or a cutting-edge protocol. Just a higher dose of something most people on this channel already know.

But before you draw any conclusions from that, there is something about how hair count studies work that changes how you should read those numbers. Most people covering this trial skip over it entirely. Andrew doesn't.

He also gets into what the scalp tissue data revealed that the bloodwork completely missed, what the side effect numbers actually mean when you look at the full context, and whether any of this points toward a smarter approach than simply raising the dose.
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20 Comments

@hansgruber2509 8 days ago

That is a 20 year old study, have the results been replicated in the last decade?

@kondor6120 7 days ago

I was taking oral minoxidil (2.5 mg/ed) and dutasteride (0.5 mg/ed); I’m seeing improvement after adding topical minoxidil (10%) and dutasteride (0.1%). No side effects.

@Kwak-Kwak_Marcos-Jr 8 days ago

Taking daytime of oral minoxidil show significant result compare to that take evening in new study published by 'British Association of Dermatologist ' on July 15 2026.

@Samfrancis0000 8 days ago

Wait do you guys make a compounded 2.5mg?

@paulo8798-s6f 4 days ago

Do you plan to make your products like slow release minoxidil and topical dutasteride available in Europe ?

@ytrebiLeurT 6 days ago

The active ingredient in Finasteride is Macrogol 6000, which is a laxative; how can a laxative make hair grow back?
Ingredients of Finasteride:
Lactose monohydrate, Lactose, Microcrystalline cellulose, Pregelatinised maize starch, PEG-32 glycerol laurate
Sodium starch glycolate (Type A), Magnesium stearate (vegetable origin), Hypromellose (6 mPa·s), Titanium dioxide,
Iron(III) oxide, Black iron(III) oxide hydrate, Macrogol 6000

@valentinopichara 2 days ago

I think lower dosis like 0.1 or 0.2 MG plus meso with dutasteride prp and vitamins . Results goes in low sides effects to 0 and you can see your hair grow very well darker and stronger

@Whitbykarate 8 days ago

Too bad we can’t get your formulation in Canada.

@jazzskunk91 7 days ago (edited)

I lost my crown from switching off of finasteride for seven years to dutasteride over the course of a year and a half of use.
I can't reason why with all these positive studies. I just don't think my genetics respond well to dutasteride.

@dylandempster1680 7 days ago

Really appreciate videos like this man thanks 👍🏻

@monecayardley 7 days ago

I use #liquidbiocellcollagen2012 for 14 years Got me through 4x hair loss and thinning. Hair breaks. Hair back to bra line thick and lustre. Phew. 65YO. Been testing since 2012.
Stop eating sugar and seed oils. Eat beef for b12. Respectfully Moneca 65YO #CollagenBabe #Carnivore2024 #LiquidBiocellCollagen2012 🙏🧠❤️🥩🇨🇦✨

@brunovercosa7119 7 days ago

Wouldn’t it make more sense to have a topical 2.5mg dudasteride?

@Dyegopires761 7 days ago

Will switching from oral finasteride to topical finasteride or dutasteride cause temporary hair loss?

@rhdrhd3255 5 days ago

And prostate cancer increase by how much ?

@Mayeankkhatter 7 days ago

Who will tell the side effects in body mood related things. My finasteride experience was really bad

@TuranCahangirov 6 days ago

Minoksidil sprey iki yilda seyreklesmiş saçlari geri çikarirmi? Kökler var sa?

@GottaBeMatt 2 days ago

Do you think I should start taking 2.5mg? I’ve been on 0.5mg for 2 years and haven’t stabilised at all. Also on RU and oral minox.

@ytrebiLeurT 6 days ago

So, these are the ingredients of 0.5 mg dutasteride:
butylhydroxytoluene, glycerol monocaprylocaprate, gelatin, glycerol, titanium dioxide, yellow iron(III) oxide hydrate,
medium-chain triglycerides, deoiled soybean phospholipids, purified water.
"Butylated hydroxytoluene (BHT) is a chemical compound belonging to the classes of toluene derivatives and phenols; it is produced and used industrially in significant quantities. Phytoplankton such as the green alga Botryococcus braunii and the cyanobacteria Cylindrospermopsis raciborskii*, *Microcystis aeruginosa*, and *Oscillatoria sp. produce BHT, as demonstrated by GC-MS."

@MichaelS-e8z 2 days ago

Some questions: 1. Why even quote studies with a sample size of 60-70? "Sample size neglect" due to high variance, make these studies not very compelling. You have to have at least about 500 people in the study to counteract that. 2. Dutasteride was known to have a half-life of about five weeks, so overloading your body with it probably does not yield significant benefits. 3. Topical probably shows promise but has anyone considered if dustasteride in your eyes or ears might be harmful? It will inevitably find its way there when you shower. 4. Why do you spend so much time discussing low libido as a negative side-effect? A man with low libido is a man that has much more control over his life. The decisions he will make will be legitimately based on his free will, not on attracting female attention.
In any event, I doubt that dutasteride has much effect on libido, but if you are worried about it, exercising, doing weight bearing activities, will more than offset that.