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Ranking Isaac's BEST and WORST Secret Room Items

Another Matt Playing Isaac

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EDIT by Pupzel ► https://x.com/PupzelPup

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The Binding of Isaac Repentance, Repentance PLUS +, Rebirth, Afterbirth, Afterbirth+, whatever else there is is meant to be played one way. I did it the opposite way i'm pretty sure. Anyways no polyphemous, C Section, Brimstone, Mom's Knife, Haemolacrea crazy broken build run here. Only Isaac and his mad hops

#bindingofisaac #isaac #gaming #tierlist

20 Comments

@PieToast 1 year ago

never let chat cook again

@1stnamel4stname 1 year ago

This convinced me that 60%+ of your chat have never installed the game

@quantumcraze2131 1 year ago

Sorry matt, binge eater gives you -0.03 speed for every food item consumed not -0.30 speed. A very simple mistake but unfortunately, this video is now unwatchable :(

@danieldash6661 1 year ago (edited)

not giving death certificate s+ considering it can give a s+ item is crazy

p.s iam joking great vid as always

@LimboEffugiumWritter 1 year ago

Are you sure E D6 is 50%?
From what I remembered, it is 25% and only goes up to 50 if you have car battery.
I've played the lost a lot and I'm convinced items weren't getting destroyed half of the time.
I think I also remember Hutts saying "look, the game says it's 25%, but we all know in our hearts that it's not 25%"

@pupzelpup9136 1 year ago

38:31 the humble black screen, classic

@T.G.Phoenix 1 year ago

As a Magic the Gathering player: discussions about altering Black Lotus are a nonstarter. It would make 0 sense as a cultural reference if altered.

@neros_soren 2 months ago

Changing Black Lotus to giving every heart would ruin the reference.

@JackRaven-u5m 1 year ago

GB bug is S+ because if you get it from modelling clay you have an infinite that lasts for about four straight hours and saves a gauntlet run. I'm sure Matt's opinion about GB bug's rerolls has changed since this tier list :P

@stevenharvey8831 1 year ago

Matt giving strawman revelation as T.Issac then setting him down and deleting revelation will not be forgotten

@dragonlord4898 1 year ago

27:57 it is 50/50. You either get it, or you don’t

@carterhugs 8 months ago

Black lotus gives 3 hearts because it’s a reference to the MTG card that grants 3 mana

@boyfriend1161 2 days ago

Can someone explain to me why is key bum so low? Isn't that just guppy's tail?

@thelongarmlady 11 months ago

14:06 echo chamber, vurp, stat up pill is very fun :)

@benro6564 1 year ago

Esau JR below book of secrets is insane

@Beebops_Handle 1 year ago

my guess is that items are going to either S+ or F no inbetween

@greengreen110 1 day ago

Even ignoring the teleportation effect, cursed eye is the only charge to shoot in the game that can't justify itself. Its best sinergies are with items that override it and it's like almost barely a damage up, never take this item. It's only real purpouse is to punnish you for entering curse rooms with curse of the blind.

@Marsquatch-z7l 1 year ago

I love that every time Matt talks about Spindown Dice he talks as if Platinum God doesn’t exist

@bingoviini 1 year ago

Skinny odd shroom is just a way less extreme soymilk
And thus has all the same problems as soymilk, without any of the extreme synergies that soymilk has