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Would I Recommend Berberine After 50?

Richard Kelley M.D.

75,716 views

👉 Would I Recommend Berberine After 50?

Berberine has become one of the most talked-about supplements for blood sugar, insulin resistance, weight loss, and metabolic health. But what does the latest research actually show?

In this video, I review the newest evidence, including systematic reviews and meta-analyses, to separate the science from the hype. We'll discuss what berberine may help with, where the evidence is strongest, where important questions remain, and who should be cautious before taking it.

As always, my goal isn't to tell you what to take—it's to help you better understand the evidence so you can make more informed decisions about your health.

Disclaimer: This video is for educational purposes only and is not intended as personal medical advice. Always discuss changes to your medications or supplement regimen with your healthcare provider.

📚 Research referenced in this video: 👇
👉 https://www.clinicaltherapeutics.com/...
👉 https://pmc.ncbi.nlm.nih.gov/articles...
👉 https://pmc.ncbi.nlm.nih.gov/articles...
👉 https://pubmed.ncbi.nlm.nih.gov/40972...

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👉 DISCLOSURE: I am the founder of this supplement brand and have a financial interest in this business.
The information on this channel is for educational purposes only and is not a substitute for medical advice.
Dietary supplements discussed in this video — including those in my supplement line — are not intended to diagnose, treat, cure, or prevent any disease.
Always consult your healthcare provider before starting any new supplement or medication.
🛒 My Supplement Line:
👉 https://www.DoctorsSupplementPortal.com

👉 For More Information, visit my website at: https://richardkelleymd.com/

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20 Comments

@esskeller9676 2 months ago

I get more info from the comments than the video.

@stevehumble8865 1 month ago (edited)

I am in the early experimental phase of using berberine. I've been taking 500mg twice a day for about a month. Here is what I've noticed so far - my blood pressure numbers have come down to the equivalent numbers of using Amlodopine. I had to actually stop my BP medication for a few weeks because of negative side effects. Berberine has lowered my numbers enough that I now question whether I should even be using BP medication at all.
Benefit #2- my night time bathroom trips have stopped almost completely! I have an enlarged prostate and I usually go 2 to 3 times during the night. Now, in just a few weeks on berberine I don't go to the bathroom until around 4 am. I am very happy so far with what berberine has done for my health issues.
I will be seeing my urologist and my regular doctor soon, so I am not trying to do this all on my own.

Update: (one month from original post) I just had bloodwork done this week and my cholesterol number went down, triglycerides went down, good cholesterol up (by 1 point), and surprisingly my PSA number has lowered. The only thing different I have done since the last bloodwork 6 months ago is take berberine along with a dramatic reduction in consuming bacon and butter.

@HenchmanNumber1-e8q 2 months ago

They can study this stuff until the cows come home and we will still be seeing and hearing the same things. One doctor says this. Another doctor says that. On and on. If we wait until there is incontestable proof we will be waiting until our life is done. If it seems to help reduce glucose spikes then that is enough for me. It does seem to do that or is at least helpful.

@christinethomas6668 2 months ago

Cycling in and off of Berberine has helped me drop 4 visceral fat points in 5 months and internal inflammation. Game-changer!

@zeevborshteen1468 2 months ago

After 3 month adding 1 gr berberine a day, a1c reduced from 6.1 to 5.9, creatinine go down from 1.44 to 1.2 , ldl from 80 to 50 , trig down to 79, blood pressure 10 point less, it is unbelievable.

@gretchenhannon7762 2 months ago

Over 70 and have taken Berberine off and on for years to help my blood sugar with good success. It lowered my triglycerides and ldl.

@Lee-d8i1b 1 month ago

I am 72 year old male. I have been taking Berberine and love all of my numbers. No side effects at all. I take the Now Foods Berberine with MCT oil soft gels

@yanyperez3609 2 months ago

I’ve never been much of a snacker and eat clean, so being “pre-diabetic” was hard to accept/understand, so I gave berberine a try. I am currently on week 3 of 1g per day. After week 1, my glucose dropped by 20-30 points consistently (as per CGM). I’m quite pleased with changes so far and look forward to other benefits that show up in time.

@judybrown4769 2 months ago

95% of all doctors have absolutely no idea how supplements work. Because they work with pharmaceutical companies they’re not looking for natural cures so is your doctor gonna tell you the truth?

@linofreek52 2 months ago

Berberine worked for me got my blood sugar down 3 points even as i introduced a few carbs back into my diet ..there is a study in fact shows an effect
on Colon cancer prevention (Physionic) i am now age 71 i think Berberine does its job quite well .

@carmenFreixas47 2 months ago

I am 80. Berberine every day

@RichardKelleyMD Creator 2 months ago (edited)

Your points are not unfounded by any means. And I think a lot of people share the same frustration with the parameters and mechanics with which the medical world operates, particularly here in the United States. Appreciate you watching the video, and taking the time to comment. Be well…and Hope you have a great week!

@alohazona173 2 months ago (edited)

I think a whole food low carb/sugar free diet,through the night sleep,fasting and consistent exercise to build muscle and mobility are a must.

@reflectionsAND 2 months ago

I love your perspective on Berberine as a pro pharmaceutical advocate/profit medical advocate. I just want to say due to negativity people like you I now have energy due to berberine. The science: It is proven science. Numerous medical journals (including the British Medical Journal and major diabetes studies) show that long-term Metformin use blocks vitamin B12 absorption in the gut, affecting up to 10% to 30% of users.
Why B12 Matters
Energy & Blood Cells: Vitamin B12 helps build red blood cells. Low levels can lead to fatigue and anemia.
Nerve Health: B12 protects your nervous system. A deficiency can cause numbness or tingling in your hands and feet. I'm so shocked I wonder why I have energy now. Why did my doctor never tell me. I won't get started on nutrition too 😅

@bryanwalsh2576 2 months ago

Ancient Chinese and Ayurvedic herbalists did ZERO clinical peer reviewed studies.

@lisaw4954 1 month ago (edited)

I take Berberine everyday a half hour before dinner. It has improved my blood sugar levels and I’ve been losing weight. I do watch what I eat and walk daily. I’ve been taking it for six months now.

@MrRobinGoodhand 2 months ago

Berberine can have some serious interactions with perindopril (ACE inhibitor) for blood pressure regulation. It interferes directly with some important liver enzymes which metabolize the drug, and prevents perindopril from being cleared properly. I think anybody who takes an ACE inhibitor should study berberine's specific effects before starting it. I am sure it is very good for people who are not taking blood pressure medication.

@beckysmith1178 2 months ago

I'm a retired nurse, so like so many nurses with a family I was not taking good care of myself. Working night shift for almost 40yrs with poor sleep and no real exercise and poor diet, eating on the run. So being over weight and obese BMI. Once I retired and was 65yrs of age my doctor was concerned about my weight and labs showing elevated cholesterol markers. I started on Berberine ( taking berberine HCl in the form of berberis arista bark 1200mg total a day 600mg BID) on my own taking numerous other supplements in an attempt to boost my immune system and in hopes of lowering my cholesterol (after the Covid scare). Even though I really didn't increase my exercise by a lot (I did walk purposely but not as much as needed), I still was basically sedentary (thinking that I deserved to finally rest) eating less but still not really as healthy as I knew to eat as a nurse. My doctor was quickly impressed by my cholesterol markers going down to an acceptable level. He still wasn't happy about my weight even with a 10lb weight loss from 234 to 224. My main question is what form of Berberine is the best and if the one that I am taking is of good quality? Since I have had good results I am not making any changes in this brand supplement of Berberine at a cost of around $32.00 a bottle for a 60 count. Thanks for your informative video but I didn't hear you answer the question if a person over 50 should be taking it as your video was titled.