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Can we take too many “mitochondrial enhancers?” What happens when we start using compounds our bodies may not actually need?

Peptides. Injectables. Mitochondrial agents. Biohacking is exploding—but are these tools solving real problems… or creating new ones?

In this episode, I sat down with researcher, coach, and educator Jake Benson for a deep dive into methylene blue, mitochondrial health, and a bigger question:

How should we think about using any compound—whether for performance, health, longevity, or optimization?

This conversation goes far beyond methylene blue.

We cover:

✅ How methylene blue actually works (mechanistically and practically)
✅ Why depression and anxiety aren’t single, unified diseases
✅ Why reactive oxygen species (ROS) are essential—not just harmful
✅ Why taking a beta blocker with Clen is a terrible idea
✅ Jake’s new tool for visualizing how drugs impact the body

If you care about performance, health, longevity, PEDs, or evidence-based coaching—this one’s worth your time.

Instagram:
Instagram: ajbuuck

Jake:
Instagram: jakeyb_43

Timestamps:

0:00 – Teaser
0:27 – How the body processes food
8:46 – The role of reactive oxygen species
12:51 – The electron transport chain & methylene blue
18:53 – Using methylene blue to reduce steroid-induced elevated RBCs
22:09 – Why taking a beta blocker with Clen is a bad idea
28:59 – Why we still don’t fully understand depression & anxiety
34:11 – How methylene blue affects the body
46:16 – Why hangovers may reflect adaptive stress responses
51:18 – The best reasons to use methylene blue
58:30 – The corrosive effects of social media

#MethyleneBlue #Biohacking #Mitochondria #Longevity #Bodybuilding #PEDs #Fitness #Performance #HealthOptimization #ReactiveOxygenSpecies #Hormones #StrengthTraining #EvidenceBasedFitness #MuscleGrowth #JackedNerdPodcast